Using the PICAXE 08M2 microcontroller is a breeze. First, connect it to your system using a simple serial connection. Then, you can start programming it in the free BASIC development environment. When using it, make sure to handle the chip gently as it's a delicate electronic component. Avoid exposing it to extreme temperatures or humidity. For maintenance, keep it clean and store it in a static - free environment. If you're using it for educational purposes, explore the datasheet and other available documents to get the most out of it.