Using the HackRF One is quite straightforward. First, connect it to your computer using the provided micro USB cable. It's USB - powered, so you don't need an extra power source. You can start by using it to listen to RF emitters. If you want to transmit on ISM bands, make sure to check your country's ISM frequencies first. If you're HAM - licensed, you can take full advantage of its wide transmitting frequency range.
When programming, use the convenient buttons on the device. For synchronization, you can use the SMA female clock input and output. You can also expand its capabilities using the internal pin headers.
Remember, an antenna is not included, so get the recommended ANT500 as a starter. And since it's test equipment and hasn't been tested for regulatory compliance, you're responsible for using it legally.
In terms of maintenance, keep it in a dry and clean place. Avoid exposing it to extreme temperatures. If you're not using it for a long time, disconnect it from the USB port to save power.